{"id":25579,"date":"2022-01-21T11:58:56","date_gmt":"2022-01-21T10:58:56","guid":{"rendered":"https:\/\/cio.umh.es\/?p=25579"},"modified":"2022-01-21T11:58:56","modified_gmt":"2022-01-21T10:58:56","slug":"ena-j-segura-heras-j-v-fonseca-aizpuru-e-m-lopez-reboiro-m-l-gracia-gutierrez-a-martin-oterino-j-a-martin-urda-diez-canseco-a-perez-garcia-c-ramos-rincon-j-m-gomez-huelgas-r-2-2","status":"publish","type":"post","link":"https:\/\/cio.umh.es\/en\/2022\/01\/21\/ena-j-segura-heras-j-v-fonseca-aizpuru-e-m-lopez-reboiro-m-l-gracia-gutierrez-a-martin-oterino-j-a-martin-urda-diez-canseco-a-perez-garcia-c-ramos-rincon-j-m-gomez-huelgas-r-2-2\/","title":{"rendered":"Ena, J., Segura-Heras, J.V., Fonseca-Aizpuru, E.M., L\u00f3pez-Reboiro M.L., Gracia-Guti\u00e9rrez A., Mart\u00edn-Oterino J.A., Mart\u00edn-Urda Diez-Canseco A., P\u00e9rez-Garc\u00eda C., Ramos-Rinc\u00f3n, J.M., G\u00f3mez-Huelgas, R. (2022) \u00abDerivation and validation of a risk score for admission to the Intensive Care Unit in patients with COVID-19 | Derivaci\u00f3n y validaci\u00f3n de una puntuaci\u00f3n de riesgo de ingreso en la Unidad de Cuidados Intensivos para pacientes con COVID-19\u00bb, Revista Cl\u00ednica Espa\u00f1ola, 222 (1):1\u201312"},"content":{"rendered":"<p class=\"AuthorHeader-module__syvlN margin-size-4-t\" style=\"text-align: justify\"><strong>Javier Ena (Servicio de Medicina Interna. Hospital Marina Baixa, Alicante), Jos\u00e9 Vicente Segura (Operations Research Center, Miguel Hernandez University, Elche), Eva Mar\u00eda Fonseca (Servicio de Medicina Interna. Hospital de Cabue\u00f1es, Gij\u00f3n), Manuel Lorenzo L\u00f3pez (Servicio de Medicina Interna. Hospital P\u00fablico de Monforte de Lemos, Lugo), Anyuli Gracia (Servicio de Medicina Interna. Hospital General Defensa, Zaragoza), Jos\u00e9 \u00c1ngel Mart\u00edn (Servicio de Medicina Interna. Complejo Asistencial Universitario de Salamanca), Anabel Mart\u00edn-Urda(Servicio de Medicina Interna. Hospital de Palam\u00f3s, Girona), Cristina P\u00e9rez (Servicio de Medicina Interna. Hospital do Salnes, Vilagarc\u00eda de Arousa, Pontevedra), Jos\u00e9 Manuel Ramos (Departamento de Medicina Cl\u00ednica. Universidad Miguel Hern\u00e1ndez de Elche) and Ricardo G\u00f3mez (Departamento de Medicina Interna. Hospital Regional de M\u00e1laga. Instituto de Investigaci\u00f3n Biom\u00e9dica (IBIMA). Universidad de M\u00e1laga)<\/strong><\/p>\n<p class=\"AuthorHeader-module__syvlN margin-size-4-t\" style=\"text-align: justify\"><strong>Abstract: <\/strong>Background: This work aims to identify and validate a risk scale for admission to intensive care units (ICU) in hospitalized patients with coronavirus disease 2019 (COVID-19). Methods: We created a derivation rule and a validation rule for ICU admission using data from a national registry of a cohort of patients with confirmed SARS-CoV-2 infection who were admitted between March and August 2020 (n = 16,298). We analyzed the available demographic, clinical, radiological, and laboratory variables recorded at hospital admission. We evaluated the performance of the risk score by estimating the area under the receiver operating characteristic curve (AUROC). Using the \u03b2 coefficients of the regression model, we developed a score (0 to 100 points) associated with ICU admission. Results: The mean age of the patients was 67 years; 57% were men. A total of 1,420 (8.7%) patients were admitted to the ICU. The variables independently associated with ICU admission were age, dyspnea, Charlson Comorbidity Index score, neutrophil-to-lymphocyte ratio, lactate dehydrogenase levels, and presence of diffuse infiltrates on a chest X-ray. The model showed an AUROC of 0.780 (CI: 0.763-0.797) in the derivation cohort and an AUROC of 0.734 (CI: 0.708-0.761) in the validation cohort. A score of greater than 75 points was associated with a more than 30% probability of ICU admission while a score of less than 50 points reduced the likelihood of ICU admission to 15%. Conclusion: A simple prediction score was a useful tool for forecasting the probability of ICU admission with a high degree of precision.<\/p>","protected":false},"excerpt":{"rendered":"<p>Javier Ena (Servicio de Medicina Interna. Hospital Marina Baixa, Alicante), Jos\u00e9 Vicente Segura (Operations Research Center, Miguel Hernandez University, Elche), Eva Mar\u00eda Fonseca (Servicio de Medicina Interna. Hospital de Cabue\u00f1es, Gij\u00f3n), Manuel Lorenzo L\u00f3pez (Servicio de Medicina Interna. Hospital P\u00fablico de Monforte de Lemos, Lugo), Anyuli Gracia (Servicio de Medicina Interna. Hospital General Defensa, Zaragoza), [&#8230;]<\/p>","protected":false},"author":5675,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_links_to":"","_links_to_target":""},"categories":[369888],"tags":[],"_links":{"self":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/posts\/25579"}],"collection":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/users\/5675"}],"replies":[{"embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/comments?post=25579"}],"version-history":[{"count":0,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/posts\/25579\/revisions"}],"wp:attachment":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/media?parent=25579"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/categories?post=25579"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/tags?post=25579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}