{"id":25282,"date":"2021-10-14T09:58:37","date_gmt":"2021-10-14T07:58:37","guid":{"rendered":"https:\/\/cio.umh.es\/?p=25282"},"modified":"2022-01-14T10:00:27","modified_gmt":"2022-01-14T09:00:27","slug":"barber-x-et-al-249-2021-covid-19-in-hospitalized-hiv-positive-and-hiv-negative-patients-a-matched-study-hiv-medicine-2","status":"publish","type":"post","link":"https:\/\/cio.umh.es\/en\/2021\/10\/14\/barber-x-et-al-249-2021-covid-19-in-hospitalized-hiv-positive-and-hiv-negative-patients-a-matched-study-hiv-medicine-2\/","title":{"rendered":"Barber, X. et al. (249) (2021) \u00abCOVID-19 in hospitalized HIV-positive and HIV-negative patients: A matched study\u00bb, HIV Medicine,"},"content":{"rendered":"<p class=\"AuthorHeader-module__syvlN margin-size-4-t\"><strong style=\"font-size: 18px\">Xavier Barber (<em>University Miguel Hern\u00e1ndez of Elche<\/em>) et al.\u00a0<\/strong><\/p>\n<p style=\"text-align: justify\"><strong>Abstract:\u00a0<\/strong><span>Objectives: We compared the characteristics and clinical outcomes of hospitalized individuals with COVID-19 with [people with HIV (PWH)] and without (non-PWH) HIV co-infection in Spain during the first wave of the pandemic. Methods: This was a retrospective matched cohort study. People with HIV were identified by reviewing clinical records and laboratory registries of 10\u00a0922 patients in active-follow-up within the Spanish HIV Research Network (CoRIS) up to 30 June 2020. Each hospitalized PWH was matched with five non-PWH of the same age and sex randomly selected from COVID-19@Spain, a multicentre cohort of 4035 patients hospitalized with confirmed COVID-19. The main outcome was all-cause in-hospital mortality. Results: Forty-five PWH with PCR-confirmed COVID-19 were identified in CoRIS, 21 of whom were hospitalized. A total of 105 age\/sex-matched controls were selected from the COVID-19@Spain cohort. The median age in both groups was 53 (Q1\u2013Q3, 46\u201356) years, and 90.5% were men. In PWH, 19.1% were injecting drug users, 95.2% were on antiretroviral therapy, 94.4% had HIV-RNA &lt;\u00a050 copies\/mL, and the median (Q1\u2013Q3) CD4 count was 595 (349\u2013798) cells\/\u03bcL. No statistically significant differences were found between PWH and non-PWH in number of comorbidities, presenting signs and symptoms, laboratory parameters, radiology findings and severity scores on admission. Corticosteroids were administered to 33.3% and 27.4% of PWH and non-PWH, respectively (P\u00a0=\u00a00.580). Deaths during admission were documented in two (9.5%) PWH and 12 (11.4%) non-PWH (P\u00a0=\u00a00.800). Conclusions: Our findings suggest that well-controlled HIV infection does not modify the clinical presentation or worsen clinical outcomes of COVID-19\u00a0hospitalization<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Xavier Barber (University Miguel Hern\u00e1ndez of Elche) et al.\u00a0<br \/>\nAbstract:\u00a0Objectives: We compared the characteristics and clinical outcomes of hospitalized individuals with COVID-19 with [people with HIV (PWH)] and without (non-PWH) HIV co-infection in Spain during the first wave of the pandemic. Methods: This was a retrospective matched cohort study. People with HIV were identified by reviewing [&#8230;]<\/p>","protected":false},"author":5675,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_links_to":"","_links_to_target":""},"categories":[369888],"tags":[],"_links":{"self":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/posts\/25282"}],"collection":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/users\/5675"}],"replies":[{"embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/comments?post=25282"}],"version-history":[{"count":0,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/posts\/25282\/revisions"}],"wp:attachment":[{"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/media?parent=25282"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/categories?post=25282"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cio.umh.es\/en\/wp-json\/wp\/v2\/tags?post=25282"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}